Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 7/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592035 | 0.81 | KDM4E (0.63) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL6592031 | 0.81 | KDM4E (0.63) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL6595104 | 0.79 | KDM4E (0.51) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL6595103 | 0.79 | KDM4E (0.51) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL6668035 | 0.72 | APP (0.66) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL881864 | 0.70 | APP (0.63) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1714446 | 0.70 | RELA (0.81) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL7915381 | 0.70 | RELA (0.81) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL13467434 | 0.70 | RELA (0.81) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL3025040 | 0.70 | RELA (0.81) | MAPTMEN1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |