Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.66 |
| ▸ | MMP9 | P14780 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595479 | 0.83 | KDM4E (0.81) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL6595484 | 0.83 | KDM4E (0.81) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL7874021 | 0.79 | MMP9 (1.00) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL7219703 | 0.79 | MMP9 (1.00) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL3396274 | 0.77 | APP (0.74) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL671150 | 0.76 | TTR (0.85) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL17732299 | 0.76 | TTR (0.85) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL671149 | 0.76 | TTR (0.85) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL30807100 | 0.76 | TTR (0.85) | APPMMP9MAPTPTGS2PRKCE | |
| SCHEMBL10766293 | 0.74 | APP (0.70) | APPMMP9MAPTPTGS2PRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |