Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663884 | 1.00 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6660882 | 0.84 | IP6K1 (0.46) | MEN1KMT2AKDM4EALDH1A1IP6K1 | |
| SCHEMBL6660879 | 0.84 | IP6K1 (0.46) | MEN1KMT2AKDM4EALDH1A1IP6K1 | |
| SCHEMBL8711098 | 0.80 | TAAR1 (0.38) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4067267 | 0.74 | JAK2 (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4067270 | 0.74 | JAK2 (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8705450 | 0.74 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14028465 | 0.74 | CYP1A2 (0.54) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL14919831 | 0.72 | PNP (0.31) | — | |
| SCHEMBL1240676 | 0.72 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444982-A1 | The use of purine derivatives as selective kinase inhibitors | MERCKLE GMBH (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5656264-A | ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE | SANSYO SEIYAKU CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |