SCHEMBL6663936

SCHEMBL6663936

C=CCOc1ccccc1-c1ccccc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.53
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SHMT2 P34897 1/20 0.46
LIG1 P18858 1/20 0.45
ACHE P22303 2/20 0.45
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.44
APP P05067 1/20 0.44
GAA P10253 1/20 0.43
SLC22A1 O15245 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
HTR1A P08908 1/20 0.43
CYP2D6 P10635 1/20 0.43
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764770 0.90 HPGD (0.55) HPGDTSHRMAPK1HSD17B10LIG1
1-Allyloxy-2-Methoxybenzene SCHEMBL30083991 0.86 CA12 (0.54) HPGDTSHRMAPK1HSD17B10LIG1
1-Allyloxy-2-Methoxybenzene SCHEMBL73345 0.86 CA12 (0.54) HPGDTSHRMAPK1HSD17B10LIG1
SCHEMBL6665177 0.82 SYK (0.56) HPGDTSHRMAPK1HSD17B10SHMT2
SCHEMBL28538424 0.80 MAPT (0.50) HPGDTSHRMAPK1HSD17B10LIG1
SCHEMBL8637600 0.80 LIG1 (0.47) HPGDTSHRMAPK1HSD17B10LIG1
SCHEMBL28547491 0.80 HPGD (0.46) HPGDTSHRMAPK1HSD17B10LIG1
1,2-Diallyloxybenzene SCHEMBL29768784 0.80 HPGD (0.60) HPGDTSHRMAPK1HSD17B10LIG1
1,2-Diallyloxybenzene SCHEMBL366516 0.80 HPGD (0.60) HPGDTSHRMAPK1HSD17B10LIG1
SCHEMBL515196 0.79 ADRB2 (0.59) HTR7HPGDTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004024684-A2 ENANTIOSELECTIVE AMINATION AND ETHERIFICATION YALE UNIVERSITY (US) 2004-03-25 WO disclosed