Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359120 | 0.82 | SLC6A4 (0.44) | MAPTTDP1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL14523920 | 0.82 | ELANE (0.44) | MAPTTDP1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL9359123 | 0.81 | MEN1 (0.43) | MAPTTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL9359242 | 0.81 | MEN1 (0.43) | MAPTTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL9359128 | 0.81 | MEN1 (0.43) | MAPTTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL6662868 | 0.79 | CES2 (0.53) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL6666273 | 0.79 | CES2 (0.44) | MAPTTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL6664998 | 0.77 | L3MBTL1 (0.44) | MAPTTDP1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL6667274 | 0.77 | ELANE (0.42) | MAPTTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL24157322 | 0.76 | MAPT (0.70) | MAPTTDP1L3MBTL1KIF11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |