Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.68 |
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL10823259 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1008761 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL9253149 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL3163862 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL20704875 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL10898181 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL6664068 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1010631 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL21958268 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL3044026 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727608-B1 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO LTD (JP) | 2004-09-01 | — | — | EP | claimed |
| US-5862796-A | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1999-01-26 | — | — | US | claimed |
| EP-0727608-A2 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1996-08-21 | — | — | EP | claimed |
| CN-103386303-B | A kind of hydrogenation catalyst and preparation method thereof | SINOPEC CORP. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-102698744-B | Sandwich cylindrical catalyst and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2014-07-23 | — | — | CN | disclosed |
| CN-103386303-A | Hydrogenation catalyst and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2013-11-13 | — | — | CN | disclosed |
| CN-102139211-B | Method for preparing noble metal/TiO2-C catalyst for hydrofining of crude terephthalic acid | CHINA PETROLEUM & CHEMICAL | 2013-02-13 | — | — | CN | disclosed |
| EP-0727608-B1 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| CN-1062492-C | Process for reclaiming waste catalyst with low palladium content | WEI SHIPING (CN) | 2001-02-28 | — | — | CN | disclosed |
| US-5998647-A | BIPHENYL DICARBOXYLIC ACID COPPER COMPLEX | OSAKA GAS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5862796-A | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| CN-1186718-A | Process for reclaiming waste catalyst with low palladium content | WEI SHIPING (CN) | 1998-07-08 | — | — | CN | disclosed |
| EP-0727608-A2 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |
| EP-0019483-B1 | METHOD OF PRODUCING BIPHENYLTETRACARBOXYLIC ESTERS | UBE INDUSTRIES, LTD. (JP) | 1982-09-29 | — | — | EP | disclosed |
| US-4338456-A | PALLADIUM SALT CATALYST | UBE INDUSTRIES, LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4294976-A | DEHYDROGENATIVE DIMERIZATION IN THE PRESENCE OF OXALIC ACID AND A PALLADIUM CATALYST | UBE INDUSTRIES, LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4292435-A | PREFERENTIAL COUPLING OF THE PHENYL DIALKYL ESTER USING A CATALYST OF A PALLADIUM COMPOUND AND 1,10-PHENANTHROLINE | UBE INDUSTRIES, LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| EP-0019483-A1 | Method of producing biphenyltetracarboxylic esters | UBE INDUSTRIES, LTD. (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-3940426-A | CRYSTALLIZATION OF ISOMERS | UBE INDUSTRIES, LTD. (JA) | 1976-02-24 | — | — | US | disclosed |