Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664087 | 0.98 | MAPK1 (0.60) | MAPK1MAOBMAPTKDM4EALDH1A1 | |
| SCHEMBL1616064 | 0.82 | MAPK1 (0.57) | MAPK1MAOBALDH1A1SLC6A3CA1 | |
| SCHEMBL1616428 | 0.82 | MAPK1 (0.57) | MAPK1MAOBMAPTKDM4EALDH1A1 | |
| SCHEMBL1616066 | 0.82 | MAPK1 (0.57) | MAPK1MAOBALDH1A1SLC6A3CA1 | |
| SCHEMBL1616429 | 0.82 | MAPK1 (0.57) | MAPK1MAOBMAPTKDM4EALDH1A1 | |
| SCHEMBL6666145 | 0.82 | MAPK1 (0.57) | MAPK1MAOBMAPTKDM4EALDH1A1 | |
| SCHEMBL15684281 | 0.79 | SIGMAR1 (0.52) | MAPTL3MBTL1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL945418 | 0.78 | MAOB (0.48) | MAPK1MAOBMAPTKDM4EALDH1A1 | |
| SCHEMBL12230208 | 0.78 | MAPK1 (0.52) | MAPK1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16226133 | 0.77 | MAPK1 (1.00) | MAPK1MAPTKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |