Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664833 | 0.84 | MAOB (0.58) | AGXTMAOBLTA4HCA1CA2 | |
| SCHEMBL6667094 | 0.82 | MAOB (0.54) | AGXTMAOB | |
| SCHEMBL6666194 | 0.78 | APP (0.43) | MAOB | |
| SCHEMBL4396682 | 0.77 | CYP1A2 (0.55) | PTGER4FFAR1FFAR4 | |
| SCHEMBL4394404 | 0.77 | CYP1A2 (0.55) | PTGER4FFAR1FFAR4 | |
| SCHEMBL2360573 | 0.72 | LTA4H (0.53) | MAOBLTA4H | |
| SCHEMBL6664995 | 0.72 | MAOB (0.48) | MAOBCA1CA2ARG2 | |
| SCHEMBL9618106 | 0.72 | MAOB (0.43) | AGXTMAOBNR4A2LTA4HCA1 | |
| SCHEMBL6666271 | 0.72 | MAOB (0.48) | MAOBLTA4HCA1CA2ARG2 | |
| SCHEMBL2360572 | 0.72 | LTA4H (0.53) | MAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |