Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360573 | 0.85 | LTA4H (0.53) | MAOBSIGMAR1GPR52G6PC1KDM4E | |
| SCHEMBL2360572 | 0.85 | LTA4H (0.53) | MAOBSIGMAR1GPR52G6PC1KDM4E | |
| SCHEMBL6665182 | 0.83 | LTA4H (0.52) | MAOBIDO1AGXTSIGMAR1KDM4E | |
| SCHEMBL6664833 | 0.82 | MAOB (0.58) | MAOBIDO1AGXTKMT2A | |
| SCHEMBL6664124 | 0.82 | AGXT (0.46) | MAOBAGXT | |
| SCHEMBL6666194 | 0.80 | APP (0.43) | MAOBALDH1A1KMT2A | |
| SCHEMBL28084246 | 0.78 | IDO1 (0.56) | MAOBIDO1AGXTSIGMAR1TAAR1 | |
| SCHEMBL28140894 | 0.77 | RELA (0.56) | MAOBG6PC1 | |
| SCHEMBL6666271 | 0.75 | MAOB (0.48) | MAOBGPR52HTTSMN1; SMN2MEN1 | |
| SCHEMBL29288278 | 0.74 | GRIN1 (0.56) | MAOBIDO1AGXTSIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |