Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.53 |
| ▸ | MTTP | P55157 | 12/20 | 0.47 |
| ▸ | APOB | P04114 | 12/20 | 0.47 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804749 | 0.92 | SMO (0.64) | SMOMTTPAPOB | |
| SCHEMBL6667139 | 0.87 | SMO (0.52) | SMOMTTPAPOB | |
| SCHEMBL6664848 | 0.84 | HTR2A (0.53) | SMOMTTPAPOBSRPK1SORT1 | |
| SCHEMBL6663338 | 0.81 | HTR2A (0.53) | SMOMTTPAPOBSORT1 | |
| SCHEMBL6669784 | 0.80 | SMO (0.53) | SMOMTTPAPOBSRPK1SORT1 | |
| SCHEMBL6635095 | 0.79 | PARP1 (0.48) | SMOMTTPAPOBSRPK1SORT1 | |
| SCHEMBL6799538 | 0.79 | SMO (0.63) | SMOMTTPAPOB | |
| SCHEMBL7086991 | 0.78 | SMO (0.48) | SMOMTTPAPOBSORT1 | |
| SCHEMBL6666524 | 0.78 | SMO (0.51) | SMOMTTPAPOBSRPK1SORT1 | |
| SCHEMBL6664745 | 0.78 | EIF2AK3 (0.46) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |