Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | HTR2B | P41595 | 5/20 | 0.53 |
| ▸ | SMO | Q99835 | 3/20 | 0.51 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.43 |
| ▸ | MTTP | P55157 | 3/20 | 0.43 |
| ▸ | APOB | P04114 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663338 | 0.94 | HTR2A (0.53) | HTR2AHTR2CHTR2BSMOMTTP | |
| SCHEMBL6664745 | 0.91 | EIF2AK3 (0.46) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6804688 | 0.91 | SMO (0.61) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6804505 | 0.91 | SMO (0.52) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6805171 | 0.90 | SMO (0.52) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6646377 | 0.90 | HTR2A (0.55) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6664314 | 0.90 | SMO (0.47) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6667572 | 0.89 | HTR2A (0.43) | HTR2AHTR2CHTR2BSMOEIF2AK3 | |
| SCHEMBL6663855 | 0.88 | SRPK1 (0.43) | HTR2AHTR2CHTR2BSMOSRPK1 | |
| SCHEMBL6665118 | 0.88 | RIPK1 (0.43) | HTR2AHTR2CHTR2BSMOEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | claimed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | claimed |
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |