Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MTTP | P55157 | 2/20 | 0.45 |
| ▸ | APOB | P04114 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788407 | 0.90 | SMO (0.59) | SMOPOLBMTTPAPOBKDM4E | |
| SCHEMBL7084308 | 0.87 | SMO (0.49) | SMOMTTPAPOBSORT1RXFP1 | |
| SCHEMBL7083654 | 0.86 | SORT1 (0.45) | SMOMTTPAPOBSORT1RXFP1 | |
| SCHEMBL6638865 | 0.80 | SMO (0.53) | SMOMTTPAPOBSORT1RXFP1 | |
| SCHEMBL7086824 | 0.79 | LMNA (0.48) | SMORXFP1LMNAALDH1A1KMT2A | |
| SCHEMBL7083387 | 0.79 | SMO (0.49) | SMOSORT1RXFP1LMNAALDH1A1 | |
| SCHEMBL6639807 | 0.79 | SMO (0.49) | SMOMTTPAPOBSORT1RXFP1 | |
| SCHEMBL7160923 | 0.78 | TRPV1 (0.48) | RXFP1LMNAALDH1A1KMT2ATRPV1 | |
| SCHEMBL6664137 | 0.78 | SMO (0.53) | SMOMTTPAPOBSORT1 | |
| SCHEMBL6792281 | 0.78 | SMO (0.62) | SMOMTTPAPOBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |