Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ADH1B | P00325 | 1/20 | 0.54 |
| ▸ | ADH1C | P00326 | 1/20 | 0.54 |
| ▸ | ADH1A | P07327 | 1/20 | 0.54 |
| ▸ | ADH7 | P40394 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666155 | 0.85 | HTT (0.53) | MAOBALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29798082 | 0.84 | ADH1B (0.65) | ADH1BADH1CADH1AADH7CA2 | |
| SCHEMBL8713797 | 0.84 | ADH1B (0.65) | ADH1BADH1CADH1AADH7CA2 | |
| SCHEMBL1101278 | 0.81 | ADH1B (0.52) | MAOBADH1BADH1CADH1AADH7 | |
| SCHEMBL887919 | 0.81 | ADH1B (0.52) | MAOBADH1BADH1CADH1AADH7 | |
| SCHEMBL8162959 | 0.81 | ADH1B (0.52) | MAOBADH1BADH1CADH1AADH7 | |
| SCHEMBL6014393 | 0.79 | ADH1B (0.50) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL6014397 | 0.79 | ADH1B (0.50) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL6668268 | 0.78 | MAOB (0.52) | MAOBADH1BADH1CADH1AADH7 | |
| SCHEMBL13256428 | 0.78 | MAOB (0.52) | MAOBADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112592310-B | 2-hydroxypyridine compound and synthetic method thereof | 南京工业大学 | 2022-04-29 | — | — | CN | disclosed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |