SCHEMBL6668268

SCHEMBL6668268

C=CCNC=CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ARG2 P78540 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH7 P40394 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TOP1 P11387 1/20 0.35
KCNH2 Q12809 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
LMNA P02545 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6664295 0.78 MAOB (0.58) MAOBCA1CA2ARG2MAPT
SCHEMBL4631658 0.76 MAOB (0.62) MAOBCA1CA2ARG2GAA
SCHEMBL4084680 0.74 SUMO3 (0.43) MAOBMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL13256428 0.73 MAOB (0.52) MAOBCA1CA2ARG2MAPK1
SCHEMBL8074750 0.73 MAOB (0.71) MAOBCA1CA2ARG2GAA
SCHEMBL8074747 0.73 MAOB (0.71) MAOBCA1CA2ARG2GAA
SCHEMBL472992 0.72 ALDH1A1 (0.41) MAOBGAAMAPTSMN1; SMN2ALDH1A1
Allylbenzene SCHEMBL10325179 0.71 MAOB (0.60) MAOBCA1CA2ARG2GAA
Allylbenzene SCHEMBL2478260 0.71 MAOB (0.60) MAOBCA1CA2ARG2GAA
Allylbenzene SCHEMBL21274 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004024684-A2 ENANTIOSELECTIVE AMINATION AND ETHERIFICATION YALE UNIVERSITY (US) 2004-03-25 WO disclosed