Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668914 | 0.90 | L3MBTL1 (0.37) | LMNAMAPK8THRBMAPTALDH1A1 | |
| SCHEMBL21034417 | 0.84 | LMNA (0.46) | LMNAMAPK8CARM1MAPTALDH1A1 | |
| SCHEMBL21034418 | 0.82 | MAPK8 (0.44) | LMNAMAPK8HTR1ADRD2ADRA1A | |
| SCHEMBL6666269 | 0.81 | MAPT (0.38) | LMNAMAPK8CARM1MAPTALDH1A1 | |
| SCHEMBL3250748 | 0.81 | MAPK8 (0.43) | LMNAMAPK8HTR1ADRD2ADRA1A | |
| SCHEMBL22488063 | 0.81 | MAPK8 (0.43) | LMNAMAPK8HTR1ADRD2ADRA1A | |
| SCHEMBL6592805 | 0.80 | LMNA (0.60) | LMNAMAPTALDH1A1GAATSHR | |
| SCHEMBL21034409 | 0.79 | LMNA (0.48) | LMNAMAPK8THRBMAPTGAA | |
| SCHEMBL21034914 | 0.78 | MEN1 (0.43) | LMNAMAPK8THRBMAPTALDH1A1 | |
| SCHEMBL3955026 | 0.78 | ATM (0.42) | LMNAMAPK8HTR1ADRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | claimed |