Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659004 | 0.96 | POLB (0.43) | POLBNPSR1KMT2AMAPK1HPGD | |
| SCHEMBL8728627 | 0.95 | POLB (0.43) | POLBNPSR1KMT2ACETP | |
| SCHEMBL6662510 | 0.92 | POLB (0.47) | POLBNPSR1KMT2AMAPK1HPGD | |
| SCHEMBL6667602 | 0.86 | POLB (0.49) | POLBNPSR1KMT2AMAPK1HPGD | |
| SCHEMBL6658782 | 0.81 | NPSR1 (0.43) | POLBNPSR1MAPK1HPGD | |
| SCHEMBL6658790 | 0.81 | NPSR1 (0.43) | POLBNPSR1MAPK1HPGD | |
| SCHEMBL6661383 | 0.80 | GAA (0.41) | POLBNPSR1KMT2AMAPK1HPGD | |
| SCHEMBL6665628 | 0.80 | FDPS (0.44) | NPSR1CETPALDH1A1 | |
| SCHEMBL6665624 | 0.80 | FDPS (0.44) | NPSR1CETPALDH1A1 | |
| SCHEMBL6662168 | 0.79 | POLB (0.50) | POLBNPSR1KMT2AMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | claimed |
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | claimed |