Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662510 | 0.89 | POLB (0.47) | POLBNPSR1MAPK1HPGDALOX15 | |
| SCHEMBL6664553 | 0.86 | POLB (0.44) | POLBNPSR1MAPK1HPGDALOX15 | |
| SCHEMBL6659004 | 0.85 | POLB (0.43) | POLBNPSR1MAPK1HPGDALOX15 | |
| SCHEMBL8728627 | 0.84 | POLB (0.43) | POLBNPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL6662168 | 0.84 | POLB (0.50) | POLBNPSR1MAPK1HPGDALOX15 | |
| SCHEMBL6666862 | 0.84 | POLB (0.50) | POLBNPSR1MAPK1HPGDALOX15 | |
| SCHEMBL6662872 | 0.83 | ACP3 (0.46) | POLBLMNAACP3 | |
| SCHEMBL8050570 | 0.83 | ACP3 (0.46) | POLBLMNAACP3 | |
| SCHEMBL6660313 | 0.77 | GAA (0.45) | POLBNPSR1TSHRMAPTALDH1A1 | |
| SCHEMBL6237835 | 0.76 | POLB (0.59) | POLBNPSR1MAPK1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | claimed |
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | claimed |