Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | FLT1 | P17948 | 8/20 | 0.40 |
| ▸ | FLT4 | P35916 | 8/20 | 0.40 |
| ▸ | KDR | P35968 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834685 | 0.75 | UTRN (0.55) | CYP1A2AHRUTRNHDAC6NPC1 | |
| SCHEMBL16459106 | 0.71 | UTRN (0.64) | CYP1A2AHRUTRNHDAC6PTGS2 | |
| SCHEMBL759091 | 0.69 | NPC1 (0.77) | NPC1PTGS2MEN1KMT2A | |
| SCHEMBL5834986 | 0.69 | RAB9A (0.56) | NPC1TOP2AMEN1KMT2A | |
| SCHEMBL6664344 | 0.69 | MAPT (0.45) | NPC1TOP2APTGS2MEN1KMT2A | |
| SCHEMBL5835069 | 0.69 | NPC1 (0.56) | NPC1PTGS2 | |
| SCHEMBL588928 | 0.68 | CA1 (0.61) | CA1CA2BRD4MEN1KMT2A | |
| SCHEMBL5834845 | 0.67 | PTGS2 (0.53) | UTRNNPC1PTGS2 | |
| SCHEMBL31154071 | 0.67 | NPC1 (0.50) | NPC1PTGS2MEN1KMT2A | |
| SCHEMBL5834493 | 0.66 | NPC1 (0.59) | HDAC6KDRNPC1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483261-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | Oxford GlycoSciences (UK) Ltd, Attn: Mary Gadsden (GB) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074516-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-09-12 | — | — | WO | disclosed |