Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR2C | P28335 | 9/20 | 0.44 |
| ▸ | HTR2B | P41595 | 5/20 | 0.42 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802137 | 0.92 | MTTP (0.47) | APOBMTTPCREBBPMAPTSMN1; SMN2 | |
| SCHEMBL6640334 | 0.87 | HTR2A (0.47) | HTR2AHTR2CHTR2BAPOBMTTP | |
| SCHEMBL6666513 | 0.87 | MTTP (0.40) | HTR2AHTR2CHTR2BAPOBMTTP | |
| SCHEMBL6667492 | 0.82 | NOTUM (0.60) | HTR2AHTR2CAPOBMTTPCREBBP | |
| SCHEMBL6805396 | 0.79 | SMO (0.47) | APOBMTTPSMN1; SMN2 | |
| SCHEMBL6669306 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2BAPOBMTTP | |
| SCHEMBL6803526 | 0.79 | MTTP (0.49) | HTR2AHTR2CAPOBMTTPTP53 | |
| SCHEMBL6665768 | 0.77 | MAPT (0.41) | HTR2AHTR2CCREBBPTP53NPC1 | |
| SCHEMBL6664419 | 0.77 | HTR2A (0.41) | HTR2AHTR2CHTR2BTP53MAPT | |
| SCHEMBL6668213 | 0.76 | AVPR2 (0.42) | TP53NPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |