Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | MTTP | P55157 | 7/20 | 0.41 |
| ▸ | APOB | P04114 | 4/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803526 | 0.91 | MTTP (0.49) | HTR2AHTR2CMTTPAPOBLMNA | |
| SCHEMBL6664562 | 0.87 | HTR2A (0.44) | HTR2AHTR2CRIPK1HTR2BMTTP | |
| SCHEMBL6665118 | 0.86 | RIPK1 (0.43) | HTR2AHTR2CRIPK1HTR2BMTTP | |
| Hydrochloric Acid SCHEMBL6666545 | 0.85 | RIPK1 (0.43) | HTR2AHTR2CRIPK1HTR2BMTTP | |
| SCHEMBL6667492 | 0.83 | NOTUM (0.60) | HTR2AHTR2CMTTPAPOBCREBBP | |
| SCHEMBL6799386 | 0.79 | SMO (0.55) | HTR2AHTR2CHTR2BMTTPAPOB | |
| SCHEMBL6802137 | 0.79 | MTTP (0.47) | MTTPAPOBCREBBPLMNAMAPT | |
| SCHEMBL6667572 | 0.79 | HTR2A (0.43) | HTR2AHTR2CRIPK1HTR2BMTTP | |
| SCHEMBL6667072 | 0.79 | MTTP (0.40) | HTR2AHTR2CRIPK1HTR2BMTTP | |
| SCHEMBL6665703 | 0.78 | CYP11B1 (0.49) | HTR2AHTR2CRIPK1HTR2BMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |