Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MTTP | P55157 | 7/20 | 0.39 |
| ▸ | APOB | P04114 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804557 | 0.92 | SMO (0.47) | MTTPAPOBSMOSMN1; SMN2KDM4E | |
| SCHEMBL6666513 | 0.89 | MTTP (0.40) | HTR2AHTR2CHTR2BMTTPAPOB | |
| SCHEMBL6665477 | 0.89 | CYP11B1 (0.38) | SMORIPK1NPC1TP53MAPT | |
| SCHEMBL6667572 | 0.88 | HTR2A (0.43) | HTR2AHTR2CHTR2BMTTPAPOB | |
| SCHEMBL6804782 | 0.86 | MAPT (0.43) | SMORIPK1NPC1TP53MAPT | |
| SCHEMBL6664848 | 0.85 | HTR2A (0.53) | HTR2AHTR2CHTR2BMTTPAPOB | |
| SCHEMBL6804333 | 0.84 | KLK7 (0.39) | SMORIPK1NPC1TP53MAPT | |
| SCHEMBL6666805 | 0.84 | CASP3 (0.43) | HTR2AHTR2CHTR2BMTTPAPOB | |
| SCHEMBL6665118 | 0.84 | RIPK1 (0.43) | HTR2AHTR2CHTR2BMTTPAPOB | |
| Hydrochloric Acid SCHEMBL6666545 | 0.83 | RIPK1 (0.43) | HTR2AHTR2CHTR2BMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |