Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | BHMT | Q93088 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597990 | 0.79 | HSD17B10 (0.77) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL6231607 | 0.79 | HSD17B10 (0.77) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL2807324 | 0.79 | HSD17B10 (0.77) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL22921976 | 0.77 | HSD17B10 (0.74) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL1323505 | 0.77 | CYP2D6 (0.67) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL8666564 | 0.76 | HSD17B10 (0.73) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL6666970 | 0.76 | CES2 (0.48) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL4649866 | 0.74 | HSD17B10 (1.00) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL1405316 | 0.74 | HSD17B10 (1.00) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL22921996 | 0.74 | MAPT (0.63) | HSD17B10GMNNTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970137-B9 | COATING, ADHESIVE AND SEALANT COMPOSITIONS | INT COATINGS LTD (GB) | 2004-09-15 | — | — | EP | disclosed |
| US-6521716-B1 | Coating, adhesive and sealant compositions | AKZO NOBEL N.V. (NL) | 2003-02-18 | — | — | US | disclosed |
| EP-0970137-B1 | COATING, ADHESIVE AND SEALANT COMPOSITIONS | INT COATINGS LTD (GB) | 2002-06-12 | — | — | EP | disclosed |