Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165362 | 0.90 | TSHR (0.54) | TSHRTHRBCHRM1DNM1CHRM2 | |
| SCHEMBL4162830 | 0.90 | TSHR (0.54) | TSHRTHRBDNM1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL1627466 | 0.89 | CHRM1 (0.41) | TSHRTHRBCHRM1DNM1CHRM2 | |
| Hydrochloric Acid SCHEMBL11323570 | 0.89 | TSHR (0.53) | TSHRTHRBDNM1POLBAPEX1 | |
| SCHEMBL3174745 | 0.86 | DNM1 (0.50) | TSHRTHRBCHRM1DNM1CHRM2 | |
| SCHEMBL4916842 | 0.86 | TSHR (0.54) | TSHRTHRBCHRM1DNM1CHRM2 | |
| SCHEMBL5804419 | 0.86 | THRB (0.47) | TSHRTHRBCHRM1DNM1CHRM2 | |
| Methacrylic Acid SCHEMBL11969913 | 0.85 | THRB (0.48) | TSHRTHRBCHRM1DNM1CHRM2 | |
| Methacrylic Acid SCHEMBL319586 | 0.85 | THRB (0.48) | TSHRTHRBCHRM1DNM1CHRM2 | |
| Bromide SCHEMBL4913238 | 0.85 | TSHR (0.52) | TSHRTHRBCHRM1DNM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045485-A1 | SUSTAINED RELEASE DOSAGE FORM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2012-02-23 | — | — | US | disclosed |