Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL11237746 | 0.94 | CA1 (0.40) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL29686938 | 0.84 | CA2 (0.53) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL6659829 | 0.84 | CA1 (0.44) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL39179 | 0.84 | CA1 (0.44) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL7567644 | 0.84 | CA1 (0.44) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL9283196 | 0.84 | CA2 (0.53) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL10608464 | 0.83 | GMNN (0.44) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL28543595 | 0.81 | CA1 (0.41) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL8639691 | 0.81 | CA1 (0.41) | CA1CA2CA7CA13ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL25292546 | 0.77 | GPR3 (0.48) | CA1CA2CA7CA13ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |