Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986994 | 0.91 | ALDH1A1 (0.43) | LMNAALDH1A1SMN1; SMN2PTPN1TSHR | |
| SCHEMBL22418856 | 0.86 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2PTPN1TSHR | |
| SCHEMBL7191735 | 0.86 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL5699531 | 0.84 | LMNA (0.42) | LMNAALDH1A1SMN1; SMN2PTPN1TSHR | |
| SCHEMBL28405833 | 0.84 | LMNA (0.48) | LMNAALDH1A1SMN1; SMN2PTPN1TSHR | |
| SCHEMBL8896279 | 0.84 | SPHK1 (0.45) | LMNACYP2D6SPHK1CYP3A4GMNN | |
| SCHEMBL1753576 | 0.83 | LMNA (0.34) | LMNATSHR | |
| SCHEMBL13625324 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2PTPN1TSHR | |
| SCHEMBL3159822 | 0.80 | LMNA (0.40) | LMNA | |
| SCHEMBL3158115 | 0.78 | LMNA (0.39) | LMNACYP2D6SPHK1CYP3A4GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230284-B1 | CURABLE COATING COMPOSITION WITH IMPROVED STABILITY | BASF CORP (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1230284-A1 | CURABLE COATING COMPOSITION WITH IMPROVED STABILITY | BASF CORPORATION (US) | 2002-08-14 | — | — | EP | claimed |
| US-6291073-B1 | UREA OR CARBAMATE AND LACTONE FOR IMPROVED STABILITY | BASF CORPORATION | 2001-09-18 | — | — | US | claimed |
| WO-2001030877-A1 | CURABLE COATING COMPOSITION WITH IMPROVED STABILITY | BASF CORPORATION (US) | 2001-05-03 | — | — | WO | claimed |
| EP-1230284-B1 | CURABLE COATING COMPOSITION WITH IMPROVED STABILITY | BASF CORP (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6291073-B1 | UREA OR CARBAMATE AND LACTONE FOR IMPROVED STABILITY | BASF CORPORATION | 2001-09-18 | — | — | US | disclosed |