Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656945 | 0.91 | MEN1 (0.48) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL6659094 | 0.91 | MAOB (0.54) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL6658434 | 0.90 | MEN1 (0.42) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL6658616 | 0.87 | MEN1 (0.51) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6657379 | 0.87 | MAPT (0.53) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6662302 | 0.86 | MAPT (0.46) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6658355 | 0.84 | ALOX5 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6659831 | 0.82 | MEN1 (0.51) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL6662202 | 0.82 | MAPT (0.60) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6659471 | 0.80 | MEN1 (0.47) | MAOBMAOAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |