Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662302 | 0.92 | MAPT (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6660189 | 0.91 | DRD2 (0.46) | ALOX5KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6658434 | 0.87 | MEN1 (0.42) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6657379 | 0.87 | MAPT (0.53) | ALOX5KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6658616 | 0.87 | MEN1 (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6664855 | 0.84 | MAOB (0.52) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6656945 | 0.83 | MEN1 (0.48) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6656820 | 0.82 | DRD2 (0.54) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6661644 | 0.81 | DRD2 (0.50) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6658201 | 0.79 | NCF1 (0.38) | ALOX5KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |