Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668373 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1POLBNPSR1HTT | |
| SCHEMBL6664326 | 0.80 | MAPT (0.60) | TDP1ALDH1A1POLBHDAC3HDAC1 | |
| SCHEMBL6667511 | 0.80 | CHRM3 (0.67) | HDAC1HDAC2L3MBTL1KMT2A | |
| SCHEMBL6679940 | 0.78 | TDP1 (0.60) | TDP1ALDH1A1POLBNPSR1HTT | |
| SCHEMBL29361009 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1NPSR1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8132848 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1NPSR1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL13233264 | 0.77 | ALDH1A1 (0.67) | ALDH1A1POLBNPSR1HTTHDAC3 | |
| SCHEMBL6668796 | 0.76 | CHRM3 (0.68) | L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL23080145 | 0.75 | ALDH1A1 (0.72) | ALDH1A1POLBNPSR1HTTHDAC3 | |
| SCHEMBL5183678 | 0.75 | ALDH1A1 (0.72) | ALDH1A1POLBNPSR1HTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |