SCHEMBL6665500

SCHEMBL6665500

Cc1cccc(C)c1COC(=O)c1ccc(C(=O)OCc2c(C)cccc2C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
ESR2 Q92731 1/20 0.53
CA14 Q9ULX7 1/20 0.53
LMNA P02545 4/20 0.49
TDP1 Q9NUW8 4/20 0.48
KMT2A Q03164 3/20 0.48
SLC6A2 P23975 2/20 0.48
MEN1 O00255 2/20 0.48
SLC6A3 Q01959 1/20 0.48
ALDH1A1 P00352 7/20 0.48
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7039710 0.95 ESR1 (0.62) ESR1CA12CA1CA2CA7
SCHEMBL6667803 0.83 TSHR (0.46) CA12CA1CA2CA7CA9
SCHEMBL605494 0.80 ALDH1A1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL13534693 0.80 SLC22A12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL6854513 0.77 ALDH1A1 (0.41) ESR1CA12CA1CA2CA7
SCHEMBL28956479 0.77 PPARG (0.56) LMNATDP1KMT2ASLC6A2MEN1
SCHEMBL27773291 0.77 KDM4E (0.55) CA12CA1CA2CA7CA9
SCHEMBL6667603 0.76 CYP4F2 (0.44) TDP1ALDH1A1KDM4EL3MBTL1HPGD
SCHEMBL3628980 0.75 ESR1 (0.61) ESR1CA12CA1CA2CA7
SCHEMBL458612 0.75 SLC22A12 (0.58) ESR1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed