SCHEMBL7039710

SCHEMBL7039710

Cc1cccc(C)c1COC(=O)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.62
ESR2 Q92731 3/20 0.62
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
LMNA P02545 4/20 0.57
ALDH1A1 P00352 3/20 0.54
TSHR P16473 3/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
KDR P35968 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
NPC1 O15118 1/20 0.53
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665500 0.95 ESR1 (0.53) ESR1ESR2CA12CA1CA2
SCHEMBL3628980 0.81 ESR1 (0.61) ESR1ESR2CA12CA1CA2
SCHEMBL6667803 0.79 TSHR (0.46) CA12CA1CA2CA7CA9
Ethylparaben SCHEMBL28326875 0.78 ESR1 (0.92) ESR1ESR2CA12CA1CA2
SCHEMBL6394260 0.78 ESR1 (0.56) ESR1ESR2CA12CA1CA2
Ethylparaben SCHEMBL5311680 0.77 CA12 (1.00) ESR1ESR2CA12CA1CA2
Ethylparaben SCHEMBL28368 0.77 CA12 (1.00) ESR1ESR2CA12CA1CA2
SCHEMBL10719857 0.76 ESR1 (0.50) ESR1ESR2CA12CA1CA2
Ethylparaben SCHEMBL23497074 0.76 CA12 (0.96) ESR1ESR2CA12CA1CA2
Ethylparaben SCHEMBL475792 0.76 CA12 (0.96) ESR1ESR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783948-B1 USED IN DIAGNOSTIC IMMUNOASSAYS; HAS DISTINCTLY DIFFERENT LIGHT EMISSION CHARACTERISTICS (EMISSION WAVELENGTH, KINETICS, OR QUANTUM YIELD) BAYER CORPORATION 2004-08-31 US disclosed