Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636325 | 0.93 | FPR2 (0.38) | SCN9AFPR2PROKR1MEN1KMT2A | |
| SCHEMBL5333712 | 0.90 | MAPT (0.36) | FPR2PROKR1MEN1KMT2ANTRK1 | |
| SCHEMBL6633908 | 0.88 | NTRK1 (0.41) | SCN9ATP53FPR2PROKR1MEN1 | |
| SCHEMBL6635325 | 0.82 | MAPT (0.45) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5339678 | 0.82 | HTR2A (0.36) | SCN9AFPR2PROKR1MEN1KMT2A | |
| SCHEMBL5331514 | 0.77 | NTRK1 (0.42) | FPR2PROKR1MEN1KMT2ANTRK1 | |
| SCHEMBL5222870 | 0.77 | MAPT (0.35) | LMNAMEN1KMT2ANTRK1 | |
| SCHEMBL5222865 | 0.77 | MAPT (0.35) | LMNAMEN1KMT2ANTRK1 | |
| SCHEMBL5221538 | 0.76 | MAPT (0.38) | LMNAMEN1KMT2ANTRK1 | |
| SCHEMBL5221796 | 0.76 | MAPT (0.36) | LMNAPROKR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487435-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077907-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2003-09-25 | — | — | WO | disclosed |