SCHEMBL666559

SCHEMBL666559

C/C=C/CCC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666560 1.00
SCHEMBL1905028 1.00
SCHEMBL955235 0.85 TSHR (0.45)
SCHEMBL2267034 0.85 TSHR (0.45)
SCHEMBL28630640 0.82 ALDH1A1 (0.50)
SCHEMBL11686907 0.80 ALDH1A1 (0.54)
SCHEMBL19361965 0.80 ALDH1A1 (0.54)
SCHEMBL13749756 0.79
SCHEMBL7998543 0.77 MAPT (0.36)
SCHEMBL10870024 0.76 PPARG (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037072-A Bionic isoprene rubber and preparation method thereof, isoprene rubber composition, isoprene rubber vulcanized rubber and application thereof 中国石油化工股份有限公司 2026-05-15 CN disclosed
EP-3354648-B1 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF CHENGDU ZENITAR BIOMEDICAL TECH CO LTD (CN) 2022-04-06 EP disclosed
US-10544134-B2 4-substituted coumarin derivatives and preparation methods and uses thereof GUIZHOU BAILING GROUP PHARMACEUTICAL CO., LTD. (CN) 2020-01-28 US disclosed
US-20180282315-A1 4-SUBSTITUTED COUMARIN DERIVATIVES AND PREPARATION METHODS AND USES THEREOF CHENGDU ZENITAR BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2018-10-04 US disclosed
EP-3354648-A1 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) 2018-08-01 EP disclosed
EP-2322529-B1 Selective glycosidase inhibitors and uses thereof UNIV FRASER SIMON (CA) 2017-12-06 EP disclosed
US-8962664-B2 Selective glycosidase inhibitors and uses thereof SIMON FRASER UNIVERSITY (CA) 2015-02-24 US disclosed
US-8648032-B2 Phenol ester as perfuming ingredient FIRMENICH SA (CH) 2014-02-11 US disclosed
EP-2437718-B1 PHENOL ESTER AS PERFUMING INGREDIENT FIRMENICH & CIE (CH) 2013-03-27 EP disclosed
US-8334310-B2 Selective glycosidase inhibitors and uses thereof SIMON FRASER UNIVERSITY (CA) 2012-12-18 US disclosed
EP-2437718-A1 PHENOL ESTER AS PERFUMING INGREDIENT Firmenich S.A. (CH) 2012-04-11 EP disclosed
US-20120045408-A1 PHENOL ESTER AS PERFUMING INGREDIENT FIRMENICH SA (CH) 2012-02-23 US disclosed
EP-2322529-A1 Selective glycosidase inhibitors and uses thereof Simon Fraser University (CA) 2011-05-18 EP disclosed
WO-2010140076-A1 PHENOL ESTER AS PERFUMING INGREDIENT FIRMENICH SA (CH) 2010-12-09 WO disclosed
US-20100016386-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2010-01-21 US disclosed
EP-2057171-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Simon Fraser University (CA) 2009-05-13 EP disclosed
WO-2008025170-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2008-03-06 WO disclosed
US-4565764-A COLORED CORE MATERIAL COATED WITH RESIN WALLS CANON KABUSHIKI KAISHA (JP) 1986-01-21 US disclosed
US-4337341-A 4a-Aryl-octahydro-1H-2-pyrindines ELI LILLY AND COMPANY (US) 1982-06-29 US disclosed
EP-0002937-A1 Novel pyrindines and their preparation, formulations and use ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed