Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233420 | 0.89 | CES2 (0.39) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL459357 | 0.89 | CES2 (0.39) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL459358 | 0.89 | CES2 (0.39) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL11819746 | 0.87 | ALDH1A1 (0.48) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL11819753 | 0.87 | ALDH1A1 (0.48) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL4400514 | 0.86 | — | — | |
| SCHEMBL8458200 | 0.86 | PPARG (0.32) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL8458198 | 0.86 | PPARG (0.32) | MAPTPPARGALDH1A1CYP19A1FFAR1 | |
| SCHEMBL4582063 | 0.86 | — | — | |
| SCHEMBL20399052 | 0.85 | FAAH (0.46) | MAPTPPARGALDH1A1CYP19A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1275985-A | Bridged fluorenyl/indenyl metallocenes and their use | PHILLIPS PETROLEUM CO (US) | 2000-12-06 | — | — | CN | disclosed |
| EP-1023298-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | Phillips Petroleum Company (US) | 2000-08-02 | — | — | EP | disclosed |
| EP-1023298-A4 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999014219-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |
| US-5886202-A | HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 1999-03-23 | — | — | US | disclosed |
| EP-0463689-B1 | Preparation of polymers of carbon monoxide with olefinically unsaturated compounds | SHELL INT RESEARCH (NL) | 1997-10-15 | — | — | EP | disclosed |
| EP-0272727-B1 | NOVEL POLYMERS OF CARBON MONOXIDE AND ALPHA-OLEFINICALLY UNSATURATED COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-10-28 | — | — | EP | disclosed |
| EP-0463689-A2 | Preparation of polymers of carbon monoxide with olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-02 | — | — | EP | disclosed |
| EP-0272727-A2 | Novel polymers of carbon monoxide and alpha-olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-29 | — | — | EP | disclosed |