Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 19/20 | 0.85 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.85 |
| ▸ | HDAC11 | Q96DB2 | 19/20 | 0.85 |
| ▸ | HDAC8 | Q9BY41 | 19/20 | 0.85 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.85 |
| ▸ | HDAC5 | Q9UQL6 | 19/20 | 0.85 |
| ▸ | HDAC7 | Q8WUI4 | 18/20 | 0.85 |
| ▸ | HDAC9 | Q9UKV0 | 18/20 | 0.85 |
| ▸ | HDAC3 | O15379 | 18/20 | 0.85 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.85 |
| ▸ | HDAC10 | Q969S8 | 18/20 | 0.85 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.85 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | BRD4 | O60885 | 1/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.85 |
| ▸ | EGFR | P00533 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | LTA4H | P09960 | 1/20 | 0.85 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137348 | 1.00 | HDAC4 (0.85) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL6669511 | 1.00 | HDAC4 (0.85) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL1065393 | 1.00 | HDAC4 (0.85) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL517309 | 0.98 | HDAC4 (0.81) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| Hydroxyamine SCHEMBL1268824 | 0.96 | HDAC6 (0.79) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL1064861 | 0.94 | HDAC4 (0.77) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL312344 | 0.94 | HDAC4 (0.77) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL6296181 | 0.93 | HDAC4 (0.75) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL23055010 | 0.92 | HDAC1 (1.00) | HDAC4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL4403514 | 0.92 | HDAC8 (0.74) | HDAC4HDAC1HDAC11HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962489-B1 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEM CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6235823-B1 | CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0557721-B1 | Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. | NEW JAPAN CHEM CO LTD (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0962489-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0557721-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |