Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.42 |
| ▸ | PGR | P06401 | 9/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657603 | 0.87 | NR3C1 (0.46) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL6664544 | 0.87 | NR3C1 (0.40) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL3658109 | 0.83 | NR3C1 (0.46) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL3652210 | 0.83 | NR3C1 (0.41) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL3717021 | 0.80 | NR3C1 (0.39) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL4468661 | 0.80 | NR3C1 (0.44) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL3741669 | 0.78 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL3658504 | 0.77 | NR3C1 (0.38) | NR3C1NR3C2PGRCYP2D6 | |
| SCHEMBL4464741 | 0.77 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL3649037 | 0.77 | NR3C1 (0.50) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |