Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664240 | 0.86 | HRH1 (0.46) | TAAR1HTR2AGAAPOLBALDH1A1 | |
| SCHEMBL6662402 | 0.85 | TAAR1 (0.41) | TAAR1HTR2AGAAPOLBALDH1A1 | |
| SCHEMBL6661785 | 0.83 | HRH1 (0.49) | TAAR1HTR2AGAAPOLBALDH1A1 | |
| SCHEMBL6661388 | 0.82 | HRH1 (0.43) | HTR2AGAAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6663343 | 0.80 | TAAR1 (0.42) | TAAR1HTR2AGAAPOLBALDH1A1 | |
| SCHEMBL7540487 | 0.80 | TAAR1 (0.44) | TAAR1HTR2AGAAPOLBALDH1A1 | |
| SCHEMBL6665209 | 0.78 | SRC (0.50) | TAAR1HTR2ALAP3ACP3GABBR2 | |
| SCHEMBL6663785 | 0.74 | DPP4 (0.43) | GAAPOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23542548 | 0.73 | ALDH1A1 (0.45) | GAAPOLBALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5750561 | 0.72 | ACP3 (0.53) | GAAPOLBALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |