Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663343 | 0.79 | TAAR1 (0.42) | ALDH1A1SMN1; SMN2TDP1LAP3GAA | |
| SCHEMBL8729170 | 0.77 | SRC (0.50) | DPP4LAP3ACP3ANPEP | |
| SCHEMBL8729175 | 0.77 | SRC (0.50) | DPP4LAP3ACP3ANPEP | |
| SCHEMBL23542548 | 0.76 | ALDH1A1 (0.45) | DPP4ALDH1A1SMN1; SMN2TDP1LAP3 | |
| SCHEMBL6665751 | 0.74 | TAAR1 (0.42) | ALDH1A1SMN1; SMN2TDP1LAP3GAA | |
| SCHEMBL31564809 | 0.73 | TDP1 (0.43) | DPP4ALDH1A1SMN1; SMN2TDP1LAP3 | |
| SCHEMBL5750561 | 0.71 | ACP3 (0.53) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL6664240 | 0.71 | HRH1 (0.46) | ALDH1A1SMN1; SMN2TDP1LAP3GAA | |
| SCHEMBL28554164 | 0.70 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TDP1GAAPOLB | |
| SCHEMBL6661785 | 0.69 | HRH1 (0.49) | ALDH1A1SMN1; SMN2TDP1LAP3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |