Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | BLM | P54132 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158251 | 0.91 | MAPT (0.72) | HIF1AMEN1GAAMAPTBLM | |
| N-Benzylaniline SCHEMBL28190059 | 0.89 | CA2 (0.62) | HIF1AMEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL5179015 | 0.89 | MAPT (0.70) | HIF1AMEN1GAAMAPTBLM | |
| Bromide SCHEMBL10436175 | 0.89 | MAPT (0.70) | HIF1AMEN1GAAMAPTBLM | |
| Hydrochloric Acid SCHEMBL7071855 | 0.83 | HIF1A (0.65) | HIF1AMEN1GAAMAPTBLM | |
| SCHEMBL6556036 | 0.83 | HIF1A (0.74) | HIF1AMEN1GAAMAPTBLM | |
| SCHEMBL9189617 | 0.82 | CA1 (0.70) | HIF1AGAAMAPTCA1CA2 | |
| SCHEMBL22776468 | 0.81 | GAA (0.74) | HIF1AMEN1GAAMAPTBLM | |
| SCHEMBL11214392 | 0.81 | CA1 (0.68) | HIF1AGAAMAPTCA1CA2 | |
| SCHEMBL28535501 | 0.81 | CA1 (0.68) | HIF1AGAAMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373726-B | A kind of preparation method of graphene | 东丽先端材料研究开发（中国）有限公司 | 2018-05-18 | — | — | CN | disclosed |
| WO-2004014328-A1 | ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS | UNILEVER PLC (GB) | 2004-02-19 | — | — | WO | disclosed |
| EP-1267809-A1 | HAIR COLOURING AND CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001076545-A1 | HAIR COLOURING AND CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-18 | — | — | WO | disclosed |