SCHEMBL6665889

SCHEMBL6665889

Cc1ccc(COC(=O)CCCCC(=O)OCc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28556266 0.94 ELANE (0.47) SMN1; SMN2L3MBTL1ENPP2ELANE
SCHEMBL8895870 0.91 SMN1; SMN2 (0.39) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL6669165 0.89 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2ALMNAL3MBTL1
SCHEMBL6667424 0.82 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2ALMNAL3MBTL1
SCHEMBL11041480 0.81 CYP4F2 (0.57) SMN1; SMN2CYP4F2CYP4A11TSHRALDH1A1
SCHEMBL11467418 0.81 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2ALMNAL3MBTL1
SCHEMBL4316026 0.81 ALDH1A1 (0.54) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL19181 0.79 CYP4F2 (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11037488 0.79 CYP4F2 (0.45) SMN1; SMN2CYP4F2CYP4A11TSHRLMNA
SCHEMBL6671495 0.77 ELANE (0.38) SMN1; SMN2HDAC8CYP4F2CYP4A11TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed