Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316026 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11467418 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6665889 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13686678 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10485097 | 0.81 | MMP1 (0.48) | SMN1; SMN2ALDH1A1HTTKDM5AKDM4C | |
| SCHEMBL6669165 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28519469 | 0.80 | ACHE (0.47) | SMN1; SMN2ALDH1A1HTTKDM4AKDM5A | |
| SCHEMBL6669050 | 0.80 | KDM4E (0.52) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL6934057 | 0.78 | TP53 (0.43) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9142113 | 0.78 | HTR2A (0.55) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |