Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661249 | 0.92 | KDM4E (0.38) | CYP11B1CYP11B2TRPV4ARKDM4E | |
| SCHEMBL6665023 | 0.88 | CYP11B1 (0.38) | CYP11B1CYP11B2TRPV4ARCACNA1H | |
| SCHEMBL6662927 | 0.87 | HSD17B10 (0.38) | TSHRHSD17B10TRPV1HTR2AFAAH | |
| SCHEMBL6663948 | 0.87 | HTR2A (0.37) | HSD17B10TRPV1HTR2AFAAHRARB | |
| SCHEMBL6662865 | 0.84 | HTR2A (0.39) | HSD17B10TRPV1HTR2AFAAHRARB | |
| SCHEMBL6666303 | 0.84 | TRPV1 (0.36) | TRPV1HTR2AFAAHRARBRARA | |
| SCHEMBL6666751 | 0.83 | HSD17B10 (0.52) | TSHRHSD17B10HTR2AFAAHKDM4E | |
| SCHEMBL6662955 | 0.83 | HTR2A (0.42) | HSD17B10TRPV1HTR2AFAAHKDM4E | |
| SCHEMBL6660713 | 0.82 | PDE2A (0.41) | TRPV1HTR2AFAAHCACNA1H | |
| SCHEMBL6661194 | 0.81 | HTR2A (0.36) | HSD17B10TRPV1HTR2AFAAHRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |