Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665296 | 0.91 | TSHR (0.40) | HSD17B10TSHRCYP19A1CYP2A6KIF11 | |
| SCHEMBL6662955 | 0.90 | HTR2A (0.42) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6661968 | 0.87 | HTR2A (0.40) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6662750 | 0.87 | HTR2A (0.40) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6661858 | 0.86 | HTR2A (0.40) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6666975 | 0.86 | FAAH (0.43) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6661170 | 0.86 | CYP2A6 (0.51) | HSD17B10TSHRCYP19A1CYP2A6KIF11 | |
| SCHEMBL6663070 | 0.85 | HTR2A (0.39) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6666058 | 0.83 | TSHR (0.36) | HSD17B10TSHRHTR2AFAAHKDM4E | |
| SCHEMBL6662927 | 0.83 | HSD17B10 (0.38) | HSD17B10TSHRHTR2AFAAHESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |