Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | EPX | P11678 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770225 | 0.82 | MEN1 (0.40) | MEN1KMT2ASCN9ACDK8TDP1 | |
| SCHEMBL29177384 | 0.82 | KMT2A (0.40) | MEN1KMT2ACHRNB2CHRNA4CCNC | |
| SCHEMBL361444 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2ASCN9ACHRNB2CHRNA4 | |
| SCHEMBL28903825 | 0.80 | MEN1 (0.38) | MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL28707710 | 0.78 | PIK3CD (0.47) | MEN1KMT2ACDK8 | |
| SCHEMBL28724684 | 0.76 | MEN1 (0.43) | MEN1KMT2ACDK8CYP1A2MPO | |
| SCHEMBL28324875 | 0.76 | SCN9A (0.37) | MEN1KMT2ASCN9A | |
| SCHEMBL28550715 | 0.76 | MAPK1 (0.38) | MEN1KMT2A | |
| SCHEMBL28595145 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2A | |
| SCHEMBL27711610 | 0.72 | NAPRT (0.46) | MEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957227-A | Pyridodiazepine derivatives as GABA Aγ1 PAM | 豪夫迈·罗氏有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-1458684-A2 | THERAPEUTIC HETEROCYCLES | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051276-A2 | THERAPEUTIC HETEROCYCLES | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |