Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236765 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL29883149 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMAP4K1LMNA | |
| SCHEMBL8771575 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMAP4K1LMNA | |
| SCHEMBL29177384 | 0.76 | KMT2A (0.40) | ALDH1A1KMT2AMEN1HPGDNNMT | |
| SCHEMBL6666490 | 0.76 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL28850118 | 0.75 | MEN1 (0.34) | ALDH1A1KMT2AMEN1MAP4K1 | |
| SCHEMBL28941018 | 0.74 | MEN1 (0.37) | ALDH1A1KMT2AMEN1MAP4K1HPGD | |
| SCHEMBL18930590 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMAP4K1LMNA | |
| SCHEMBL18921616 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1MAP4K1 | |
| SCHEMBL29882423 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473499-B | Novel pyrazolopyrimidine derivatives | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |