Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6804728 | 0.76 | HTR1F (0.94) | HTR1FRAB9AMAPTSMN1; SMN2NPC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8189875 | 0.72 | HTR1F (0.56) | HTR1FRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5906460 | 0.72 | HTR1F (0.59) | HTR1FRAB9ANPC1ACKR3HDAC1 | |
| SCHEMBL6641956 | 0.70 | HTR1F (0.81) | HTR1FRAB9ANPC1TP53CYP1A2 | |
| SCHEMBL6647888 | 0.69 | HTR1F (0.75) | HTR1FRAB9ASMN1; SMN2NPC1ACKR3 | |
| SCHEMBL8548549 | 0.67 | HTR1F (0.50) | HTR1FRAB9AMAPTSMN1; SMN2ACKR3 | |
| SCHEMBL6668295 | 0.66 | HTR1F (0.44) | HTR1FRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5906312 | 0.65 | HTR1F (0.51) | HTR1FRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6668691 | 0.65 | HTR1F (0.49) | HTR1FRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6641025 | 0.64 | HTR1F (0.71) | HTR1FMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155020-B1 | FURO[3,2-B]PYRIDINES AS 5-HT1F AGONISTS | LILLY CO ELI (US) | 2004-02-04 | — | — | EP | disclosed |