Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PPIA | P62937 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440286 | 0.87 | TSHR (1.00) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL6685980 | 0.85 | TSHR (0.71) | MAPK1TSHRMAPTMEN1GFER | |
| SCHEMBL23440297 | 0.82 | TSHR (0.75) | MAPK1TSHRMAPTMEN1GFER | |
| SCHEMBL23440311 | 0.82 | TSHR (0.80) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL23440275 | 0.81 | TSHR (0.70) | MAPK1TSHRMAPTMEN1GFER | |
| SCHEMBL6667743 | 0.81 | TSHR (0.70) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL6665288 | 0.80 | TSHR (0.77) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL23440280 | 0.80 | TSHR (0.68) | MAPK1TSHRMAPTMEN1GFER | |
| SCHEMBL6667413 | 0.79 | TSHR (0.63) | MAPK1TSHRMAPTMEN1GFER | |
| SCHEMBL12879697 | 0.78 | ALDH1A1 (0.77) | MAPK1TSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |