Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19334485 | 0.79 | KMT2A (0.59) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6667922 | 0.79 | TSHR (0.68) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6667306 | 0.79 | MAPK1 (0.76) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6685980 | 0.79 | TSHR (0.71) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL23440286 | 0.78 | TSHR (1.00) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL12879697 | 0.77 | ALDH1A1 (0.77) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6665288 | 0.77 | TSHR (0.77) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6667722 | 0.75 | TSHR (0.62) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6685181 | 0.75 | TSHR (0.70) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6667090 | 0.74 | ALDH1A1 (0.73) | TSHRMAPK1ALDH1A1MAPTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |