SCHEMBL6667358

SCHEMBL6667358

O=C(CCC(=O)OCc1cccc(Oc2ccccc2)c1)OCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.59
FFAR1 O14842 8/20 0.58
FFAR4 Q5NUL3 4/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP12 P39900 1/20 0.58
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
LMNA P02545 1/20 0.52
ADRA2A P08913 1/20 0.52
CNR1 P21554 1/20 0.52
ATM Q13315 1/20 0.52
CETP P11597 1/20 0.51
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
FDFT1 P37268 1/20 0.50
GNA15 P30679 1/20 0.49
PTGER3 P43115 1/20 0.49
AKR1C3 P42330 1/20 0.49
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20481656 0.95 FFAR1 (0.61) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL28893486 0.92 FFAR1 (0.65) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL29961732 0.92 FFAR1 (0.65) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL11321318 0.92 MMP1 (0.52) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL10417917 0.91 CETP (0.56) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL29729966 0.88 MMP1 (0.56) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL11606203 0.88 MMP1 (0.56) MMP1FFAR1FFAR4MMP2MMP9
Ethane SCHEMBL11787002 0.86 L3MBTL1 (0.63) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL9456045 0.85 MMP1 (0.49) MMP1FFAR1FFAR4MMP2MMP9
SCHEMBL28827952 0.84 MMP1 (0.59) MMP1FFAR1FFAR4MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed