SCHEMBL6667546

SCHEMBL6667546

O=C(O)CC1=CCC(=O)CC1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4536956 0.75 AKR1B1 (0.33) AKR1B1
SCHEMBL14460080 0.71 GSTP1 (0.42) AKR1B1ALDH1A1HTT
SCHEMBL16727527 0.71 AKR1B1 (0.33) AKR1B1ALDH1A1HTT
SCHEMBL4264208 0.71 CYP1A2 (0.39)
SCHEMBL6192396 0.67 AKR1B1 (0.34) AKR1B1
SCHEMBL14785349 0.63
SCHEMBL21081714 0.61 AKR1B1 (0.40) AKR1B1ALDH1A1HTT
SCHEMBL28416236 0.61 AKR1B1 (0.37) AKR1B1HTT
SCHEMBL21648094 0.61 AKR1B1 (0.37) AKR1B1ALDH1A1HTT
SCHEMBL14441021 0.60 ALDH1A1 (0.33) AKR1B1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4536465-A CONTAINING CARBOXY, OXY, AROMATIC COMPOUND AND ALDEHYDE OR KETONE WITH A NOVOLAK RESIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-20 US claimed
WO-2004024939-A2 LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR, AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY (US) 2004-03-25 WO disclosed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP disclosed
US-4536465-A CONTAINING CARBOXY, OXY, AROMATIC COMPOUND AND ALDEHYDE OR KETONE WITH A NOVOLAK RESIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-20 US disclosed
EP-0083971-A2 Photosensitive composition KONICA CORPORATION (JP) 1983-07-20 EP disclosed