SCHEMBL6667696

SCHEMBL6667696

CC(=O)Oc1ccc(COCc2ccc(OC(C)=O)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
MAPT P10636 3/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
ELANE P08246 2/20 0.50
HSD17B10 Q99714 1/20 0.48
ESR1 P03372 1/20 0.47
PGR P06401 1/20 0.47
CHRM2 P08172 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
AR P10275 1/20 0.47
CHRM1 P11229 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
HSP90AA1 P07900 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
CYP3A4 P08684 2/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033783 0.86 ALDH1A1 (0.62) LMNAMAPTPOLBPKMELANE
SCHEMBL12185174 0.86 LMNA (0.55) LMNAMAPTPOLBPKMELANE
SCHEMBL17613165 0.84 IDO1 (0.57) LMNAMAPTPOLBPKMELANE
SCHEMBL6666839 0.84 LMNA (0.53) LMNAMAPTPOLBPKMELANE
SCHEMBL10286400 0.84 LMNA (0.53) LMNAMAPTPOLBPKMELANE
SCHEMBL9081470 0.83 LMNA (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL777803 0.83 ELANE (0.62) LMNAMAPTPOLBPKMELANE
Hydrochloric Acid SCHEMBL20168290 0.82 IDO1 (0.58) LMNAMAPTPOLBPKMELANE
SCHEMBL269329 0.82 LMNA (0.80) LMNAMAPTPOLBPKMELANE
SCHEMBL134546 0.81 LMNA (0.50) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012131077-A1 SOMATOSTATIN MIMETICS NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) 2012-10-04 WO claimed
WO-2012131077-A1 SOMATOSTATIN MIMETICS NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) 2012-10-04 WO disclosed
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed